The purpose of the study was to investigate the adaptive capacity of the blood microcirculation system in children of primary school age for a functional test with heating. The article deals with the study of the blood microcirculation system in primary school children by laser Doppler flowmetry and the study of the reserve capacity of tissue blood flow in children on a test with increasing temperature factor. Materials and methods. The research was conducted on the basis of the laboratory of physiological research of the Department of Anatomy and Physiology of People and Animals of Bohdan Khmelnytsky Melitopol State Pedagogical University. The surveyed contingent consisted of 80 practically healthy children aged 6 to 9 years old, secondary school students in Melitopol. Based on a comprehensive morphofunctional study, we obtained data on individual-typological features of blood microcirculation in primary school children and the reserve capacity of tissue blood flow using functional tests. It is established that the adaptive features of the blood microcirculation system in boys and girls of early school age are due to different levels of local and central mechanisms of microvessel regulation. Results and discussion. The results obtained during the thermal test indicate different levels of reactivity of the body to increasing the temperature factor and the neurogenic vasoconstrictor effects of the sympathetic nervous system on the vessels of the arteriolar part of the microcirculatory tract. The reaction to the thermal test directly depends on the individual-typological features of blood microcirculation. Conclusion. At a ratio of reaction to thermal influence in children with various types of microcirculation, the maximum increase in tissue perfusion was observed in children with type III of laser Doppler flowgram. This level of microvascular reactivity, as well as the relatively rapid recovery of blood flow after thermal hyperemia is explained by the fact that children with hyperemic type of microcirculation have increased microvascular tone due to neurogenic effects of the sympathetic chain of tissue blood flow regulation. Children with the hypoemic type of microcirculation, on the other hand, have a somewhat reduced sympathetic tone relative to the normoemic type, as a result of which the reserve of capillary blood flow is reduced and the time of blood flow recovery after thermal exposure is prolonged

Keywords: thermal test, reactivity of the microcirculation system, laser Doppler flowmetry, primary school age

Full text: PDF (Ukr) 258K

1. Kozlov VI. Razvitie sistemy mikrotsirkulyatsii [Development of the microcirculation system]. M: RUDN; 2012. 314 s. [Russian]
2. Kozlov IO, Zherebtsov EA, Zherebtsova AI, Dunaev AV. The analysis of processing algorithms of laser Doppler signalin Lab VIEW software. Symposium Proceedings of 2 nd International Scientific Symposium «Sense. Enable. SPITSE» 2015: 225-227.
3. Kozlov VI, Sakharov VN, Gurova OA, Sidorov VV. Otsenka sostoyaniya mikrotsirkulyatsii u detei 6–7 let po dannym lazernoi dopplerovskoi floumetrii [Laser doppler flowmetry assessment of microcirculation in children of 6–7 years old]. Regionarnoe krovoobrashchenie i mikrotsirkulyatsiya. 2021; 20(3):46-53. https://doi.org/10.24884/1682-6655-2021-20-3-46-53
4. Kozlov IO, Zherebtsov EA, Podmasteryev KV. Digital Laser Doppler Flowmetry: Device, Signal Processing Technique, and Clinical Testing. Biomed Eng. 2021; 55: 12-16. https://doi.org/10.1007/s10527-021-10061-7
5. Litvin FB. Vozrastnye i individualno-tipologicheskie osobennosti mikrotsirkulyatsii u malchikov-podrostkov i yunoshey [Age and individual-typological features of microcirculation in teenage boys and boys]. Regionarnoe krovoobrashchenie i mikrotsirkulyatsiya. 2006; 5: 44-50. [Russian]
6. Gurova OA. Individualno-tipologicheskie osobennosti mikrotsirkulyatsii krovi u detey [Individually-typological features of blood microcirculation in children]. Novye issledovaniya. 2014; 2(39): 15-23. [Russian]
7. Gurova OA, Stanishevskaya TI. Reaktivnost sistemy mikrotsirkulyatsii u devushek pri teplovoy probe [Reactivity of the microcirculation system in girls with a thermal sample]. Regionarnoe krovoobrashchenie i mikrotsirkulyatsiya. 2006; 5: 58-63. [Russian]
8. Mach ES. Lazer-Dopplerfloumetriya v otsenke mikrotsirkulyatsii v usloviyakh kliniki [Laser-Dopplerfloumetria in the assessment of microcirculation in the clinic]. Materialy Pervogo Vserossiyskogo simpoziuma «Primenenie lazernoy dopplerovskoy floumetrii v meditsinskoy praktike». M; 1996. s. 56-64. [Russian]
9. Tikhomirova IA, Baboshina NV, Terekhin SS. Vozmozhnosti metoda lazernoi dopplerovskoi fluometrii v otsenke vozrastnykh osobennostei funktsionirovaniya sistemy mikrotsirkulyatsii [The possibility of the method of laser doppler fluometry in the assessment of the age features of the microcirculation system]. Regionarnoe krovoobrashchenie i mikrotsirkulyatsiya. 2019; 17(3): 80-86. https://doi.org/10.24884/1682-6655-2019-17-3-80-86
10. Anosov IP, Antonovska LV, Stanishevska TI. Metodika lazernoyi doplerovskoyi floumetriyi v otsintsi stanu mikrotsirkulyatsiyi krovi u ditey [Methods of laser doppler floosetria in assessing the condition of blood microcirculation in children]. Biologichniy visnik Melitopolskogo derzhavnogo pedagogichnogo universitetu imeni Bogdana Khmelnitskogo. 2011; 1: 6-11. [Ukrainian]
11. Dremin VV, Kozlov IO, Zherebtsov EA, Makovik IN, Dunaev AV, Sidorov VV, et al. Vozmozhnosti lazernoi dopplerovskoi floumetrii v otsenke sostoyaniya mikrogemolimfotsirkulyatsii [The possibilities of laser doppler flumetria in assessing the state of microhemolymphocyerculation]. Regionarnoe krovoobrashchenie i mikrotsirkulyatsiya. 2019; 16(4): 42-49. https://doi.org/10.24884/1682-6655-2017-16-4-42-49
12. Krupatkin AI Oscillatory processes in lymph microcirculation in the human skin. Human Physiology. 2014; 1(40):52-57. [Russian]. https://doi.org/10.1134/S0362119713040087
13. Lapach SN, Chubenko AV, Babich PN. Statisticheskie metody v mediko-biologicheskikh issledovaniyakh s ispolzovaniem Excel: 2-e izd. [Statistical Methods in Life Sciences Research Using Excel: 2th ed.]. K: MORION; 2001. 408 s. [Russian]