ISSN 2415-3060 (print), ISSN 2522-4972 (online)
  • 15 of 45
УЖМБС 2023, 8(1): 115–121
Clinical Medicine

Features of Psychopathological Symptoms in Combatants with Non-Psychotic Mental Disorders Who Had COVID-19

Koval M. Ye., Venger O. P.

The purpose of the work was to study the peculiarities of the expressiveness of psychopathological symptoms in combatants with non-psychotic mental disorders who suffered from the COVID-19 disease. Materials and methods. 252 combatants with non-psychotic mental disorders took part in the study, based on the examination of 132 combatants who did not have COVID-19 and 120 – who had COVID-19. Results and discussion. Significantly lower indicators of expressiveness of psychopathological symptoms were found in combatants who did not suffer from COVID-19, and the basis of psychopathological manifestations are: obsessive-compulsive disorders – 2.42 ± 0.33 and 2.55 ± 0.36 points, respectively (р <0.01); depression – 2.20 ± 1.15 and 2.66 ± 1.03 points (p <0.01); anxiety – 2.18 ± 0.91 and 2.41 ± 0.89 points (p <0.05). Manifestations of somatization are: auxiliary psychopathological constructs – 1.63 ± 1.07 and 2.47 ± 0.80 points (р <0.01); interpersonal sensitivity – 1.23 ± 0.96 and 1.52 ± 0.97 points, respectively (p <0.05); hostility – 1.31 ± 0.38 and 1.42 ± 0.39 points (p <0.05) and phobic anxiety – 1.23 ± 0.49 and 1.28 ± 0.48 points (p>0.05), with insignificant expressiveness of paranoid symptoms and psychoticism. It was established that combatants who suffered from the disease of COVID-19 had significantly higher levels of post-traumatic stress – 88.9 ± 16.6 and 97.8 ± 15.7 points, respectively (p <0.01), invasion symptoms – 24.5 ± 4.4 and 26.3 ± 4.9 points (p <0.01); avoidance – 23.1 ± 5.8 and 25.7 ± 5.0 points (p <0.01); excitability – 21.6 ± 5.1 and 23.8 ± 4.5 points (p <0.01); guilt – 19.7 ± 5.4 and 22.0 ± 5.0 points (p <0.01), and post-traumatic depression – 5.3 ± 4.1 and 8.2 ± 5.1 points; anxiety – 4.9 ± 3.7 and 6.8 ± 3.8 points (p <0.01), and stress – 8.1 ± 4.2 and 10.3 ± 4.1 points (p <0.01). Deterioration of cognitive functioning with a decrease in the speed and efficiency of cognitive processes was established, which did not reach the level of severe cognitive dysfunction, more pronounced in patients who suffered from COVID-19, which was manifested by a decrease in performance indicators of the TMT-A test – respectively, 37.0 ± 12.2 and 45.9 ± 14.8 sec. (p <0.01); TMT-B – 147.4 ± 37.6 and 164.4 ± 53.8 sec. (p <0.05); indicators of semantic verbal speed: number of words for letter “K” – 18.2 ± 5.4 and 16.8 ± 5.4 words (p <0.01); words for letter “P” – 16.6 ± 5.7 and 15.2 ± 5.6 words (p <0.05); words “Male names” – 17.1 ± 5.1 and 15.7 ± 5.1 words (p <0.01); words “Fruits/furniture” – 16.0 ± 5.3 and 14.7 ± 5.2 words (p <0.05), as well as slowing down the Stroop test: reading the names of colors printed in black – 51.5 ± 9.6 and 57.6 ± 8.9 sec. (p <0.01), color naming – 77.0 ± 16.9 and 86.7 ± 17.4 sec. (p <0.01), reading the names of colors where the color of the font differs from the meaning of the word – 131.2 ± 20.4 and 142.1 ± 19.9 sec., naming the color of a word where the color of the font differs from the meaning of the word – 50.5 ± 9.6 and 56.6 ± 8.9 sec. (p <0.01), stiffness/flexibility indicators of control – 54.2 ± 10.3 and 55.4 ± 7.9 sec. and verbality – 1.5 ± 0.1 and 1.5 ± 0.1 sec. Conclusion. The revealed regularities allow considering COVID-19 as an actual risk factor for the deterioration of psychopathological and post-traumatic symptoms, as well as cognitive disorders in combatants with non-psychotic mental disorders

Keywords: combatants, COVID-19, psychopathological manifestations, cognitive functioning, post-traumatic disorders

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  1. Baez S, Herrera E, Garcia A, Manes F, Young L, Ibanez A. Outcome-oriented moral evaluation in terrorists. Nat Hum Behav. 2017;1:118.
  2. Berk R. An impact assessment of machine learning risk forecasts on parole board decisions and recidivism. J Exp Criminol. 2017;13:193–216.
  3. Sommer J, Hinsberger M, Elbert T, Holtzhausen L, Kaminer D, Seedat S, et al. The interplay between trauma, substance abuse and appetitive aggression and its relation to criminal activity among high-risk males in South Africa. Addict Behav. 2017;64:29-34. PMID: 27540760; PMCID: PMC5102240.
  4. Mutamba BB, Kane JC, de Jong JTVM, Okello J, Musisi S, Kohrt BA. Psychological treatments delivered by community health workers in low-resource government health systems: effectiveness of group interpersonal psychotherapy for caregivers of children affected by nodding syndrome in Uganda. Psychol Med. 2018;48(15):2573-2583. PMID: 29444721. PMCID: PMC6093795.
  5. Porch D, Rasmussen MJ. Demobilization of paramilitaries in Colombia: Transformation or transition? Studies Conflict Terror. 2018;31(6):520-540.
  6. Zelenyj DA. Zakhysni mekhanizmy psykhiky u viysʹkovosluzhbovtsiv, yaki braly uchastʹ v ATO [Protective mechanisms of the psyche of military personnel who participated in the anti-terrorist operation]. Tezy dopovidey XVI Mizhnarodnoyi naukovoyi konferentsiyi studentiv, aspirantiv ta molodykh uchenykh “Shevchenkivsʹka vesna 2018: viysʹkovi nauki”, 2018. 2018 Mar 29. p. 33-34. [Ukrainian]
  7. Hrydkovets L, Ed. Osnovy reabilitatsiynoyi psykholohiyi: podolannya naslidkiv kryzy (navchalʹnyy posibnyk) [Basics of rehabilitation psychology: overcoming the consequences of the crisis (educational manual)]. K: Ministry of Social Policy of Ukraine2018. Vol 3. p. 27–44. [Ukrainian]
  8. Ahmed MZ, Ahmed O, Aibao Z, Hanbin S, Siyu L, Ahmad A. Epidemic of COVID-19 in China and associated Psychological Problems. Asian J Psychiatr. 2020;51:102092. PMID: 32315963. PMCID: PMC7194662.
  9. Gao J, Zheng P, Jia Y, Chen H, Mao Y, Chen S, et al. Mental health problems and social media exposure during COVID-19 outbreak. PLoS ONE. 2020;15(4):e0231924. PMID: 32298385. PMCID: PMC7162477.
  10. Mazza C, Ricci E, Biondi S, Colasanti M, Ferracuti S, Napoli C, et al. A nationwide survey of psychological distress among Italian people during the COVID-19 pandemic: immediate psychological responses and associated factors. Int J Environ Res Public Health. 2020;17:3165. PMID: 32370116. PMCID: PMC7246819.
  11. Derogatis LR, Lipman RS, Covi L. SCL-90: an outpatient psychiatric rating scale--preliminary report. Psychopharmacol Bull. 1973;9(1):13-28. PMID: 4682398
  12. Keane TM, Caddell JM, Taylor KL. Mississipi Scale for Combat-Related Posttraumatic Stress Disorder: three studies in reliability and validity. J Consult Clin Psychol. 1988 Feb;56(1):85-90. PMID: 3346454.
  13. Lovibond SH, Lovibond PF. Manual for the Depression Anxiety & Stress Scales. 2nd Ed. Sydney: Psychology Foundation; 1995.
  14. Reitan RM, Wolfson D. The Halstead–Reitan neuropsychological test battery: Theory and clinical interpretation. 2nd ed. Tucson AZ: Neuropsychology Press; 1993. 202 p.
  15. Lezak MD. Neuropsychological assessment. 3rd ed. NY: Oxford Press; 1995. 198 p.
  16. Scarpina F, Tagini S. The Stroop Color and Word Test. Front Psychol. 2017;8:557. PMID: 28446889. PMCID: PMC5388755.
  17. Reardon S. Colombia: after the violence. Nature. 2018;557:19–24. PMID: 29720642.
  18. Sheikh TL, Mohammed A, Nuhu FT, Akande Y. Coordinating psycho-social interventions for the internally displaced persons (IDPs) following insurgency in North Eastern Nigeria. Afr J Traumatic Stress. 2016;5(1):17–22.
  19. Kharchenko AO. Strukturni osoblyvosti emotsiynoyi sfery uchasnykiv boyovykh diy z poststresovoyu psykholohichnoyu dezadaptatsiyeyu [Structural features of the emotional sphere of combatants with post-stress psychological maladjustment]. Visnyk Kharkivskoho natsionalnoho pedahahichnoho universytetu imeni HS Skovorody. Seriya: «Psykholohiya». 2018;58:67–79. [Ukrainian].
  20. Yuryeva LM, Shusterman TY, Likholetov EO. Nepsykhotychni psykhichni rozlady u osib, shcho zaznaly psykhosotsialʹnoho stresu v umovakh viysʹkovoho konfliktu [Non-psychotic mental disorders in persons who experienced psychosocial stress in the conditions of the military conflict]. Medical perspectives. 2019;24(4):112-120. [Ukrainian].
  21. González-Sanguino C, Ausín B, Castellanos MA, Saiz J, López-Gómez A, Ugidos C, et al. Mental Health Consequences during the Initial Stage of the 2020 Coronavirus Pandemic (COVID-19) in Spain. Brain Behav Immun. 2020 Jul;87:172-176. PMID: 32405150. PMCID: PMC7219372.
  22. Lei L, Huang X, Zhang S, Yang J, Yang L, Xu M. Comparison of prevalence and associated factors of anxiety and depression among people affected by versus people unaffected by quarantine during the covid-19 epidemic in southwestern China. Med Sci Monit. 2020 Apr 26;26:e924609. PMID: 32335579. PMCID: PMC7199435.
  23. Wang C, Pan R, Wan X, Tan Y, Xu L, McIntyre RS, et al. A longitudinal study on the mental health of general population during the COVID-19 epidemic in China. Brain Behav Immun. 2020;87:40-48. PMID: 32298802. PMCID: PMC7153528.
  24. Wang C, Pan R, Wan X, Tan Y, Xu L, Ho CS, et al. Immediate Psychological Responses and Associated Factors during the Initial Stage of the 2019 Coronavirus Disease (COVID-19) Epidemic among the General Population in China. Int J Environ Res Public Health. 2020;17(5):1729. PMID: 32155789. PMCID: PMC7084952.
  25. Zhang Y, Ma ZF. Impact of the COVID-19 Pandemic on Mental Health and Quality of Life among Local Residents in Liaoning Province, China: A Cross-Sectional Study. Int J Environ Res Public Health. 2020;17(7):2381. PMID: 32244498. PMCID: PMC7177660.
  26. Mishra VR, Zhuang X, Sreenivasan KR, Banks SJ, Yang Z, Bernick C, et al. Multimodal MR Imaging Signatures of Cognitive Impairment in Active Professional Fighters. Radiology. 2017;285(2):555-567. PMID: 28741982. PMCID: PMC5673052.
  27. Stephen SJ, Shan G, Banks SJ, Bernick C, Bennett LL. The Relationship Between Fighting Style, Cognition, and Regional Brain Volume in Professional Combatants: A Preliminary Examination Using Brief Neurocognitive Measures. J Head Trauma Rehabil. 2020;35(3):E280-E287. PMID: 31834060.
  28. Trujillo S, Trujillo N, Lopez JD, Gomez D, Valencia S, Rendon J, et al. Social Cognitive Training Improves Emotional Processing and Reduces Aggressive Attitudes in Ex-combatants. Front Psychol. 2017;8:510. PMID: 28428767. PMCID: PMC5382221.
  29. Valk SL, Bernhardt BC, Trautwein FM, Böckler A, Kanske P, Guizard N, et al. Structural plasticity of the social brain: Differential change after socio-affective and cognitive mental training. Sci Adv. 2017;3(10):e1700489. PMID: 28983507. PMCID: PMC5627980.
  30. Bertuccelli M, Ciringione L, Rubega M, Bisiacchi P, Masiero S, Del Felice A. Cognitive impairment in people with previous COVID-19 infection: A scoping review. Cortex. 2022;154:212-230. PMID: 35780756. PMCID: PMC9187867.
  31. Henneghan AM, Lewis KA, Gill E, Kesler SR. Cognitive Impairment in Non-critical, Mild-to-Moderate COVID-19 Survivors. Front Psychol. 2022;13:770459. PMID: 35250714. PMCID: PMC8891805.
  32. Houben S, Bonnechère B. The Impact of COVID-19 Infection on Cognitive Function and the Implication for Rehabilitation: A Systematic Review and Meta-Analysis. Int J Environ Res Public Health. 2022;19(13):7748. PMID: 35805406. PMCID: PMC9266128.
  33. Tavares-Júnior JWL, de Souza ACC, Borges JWP, Oliveira DN, Siqueira-Neto JI, Sobreira-Neto MA, et al. COVID-19 associated cognitive impairment: A systematic review. Cortex. 2022;152:77-97. PMID: 35537236. PMCID: PMC90714565.