ISSN 2415-3060 (print), ISSN 2522-4972 (online)
  • 38 of 67
УЖМБС 2020, 5(4): 285–291

Comparative Assessment of Microcrystallization Index Changes of the Oral Fluid in Patients with Furuncles in Maxillofacial Region with Different Approaches of Treatment

Pohodenko-Chudakova I. O. 1, Flerjanovich M. S. 2

Furuncle is a widespread inflammatory skin disease nowadays. Issues related to the prevention and treatment of this disease are relevant not only for general surgeons, dermatologists, but also for otorhinolaryngologists, dental surgeons and maxillofacial surgeons. The purpose of the work was to evaluate the information content and the possibility to use the oral fluid microcrystallization data for monitoring the course of the inflammatory process in patients with furuncles in the maxillofacial region in standard complex of postoperative treatment and when combining with electroacupuncture treatment. Material and methods. The study involved 40 persons with maxillofacial furuncles who were divided into 2 groups. The first group (20 patients) received the standard complex treatment together with physiotherapy. The second group (20 patients) was also treated according to the standard scheme, replacing physiotherapy with a course of electro-electroacupuncture. The third group consisted of 10 practically healthy people. This group served as a control group. The indices of microcrystallization of the patients’ oral fluid was determined by I. O. Pohodenko-Chudakova, Y. M. Kazakova, N. D. Pokhodenko method (2011). Statistical data processing was performed using the "Statistica 10.0" application software package. Results and discussion. Crystallographic analysis of the oral fluid of patients who underwent a course of electroreflexotherapy in addition to the main treatment, showed that type I microcrystallization was determined in 66 quadrants (36.7%), type II was in 93 quadrants (51.7%), type III was in 21 quadrants (11.6%). The oral fluid microcrystallization index of the patients of the first group on the day of admission to hospital was 2.58 (2.42-2.75) and the patients of the second group it was 2.58 (2.50-2.75). The indicators did not have significant differences when comparing groups (U = 189.2; p = 0.90) and showed a difference with each of the above groups (U = 121.2; p = 0.03) and (U = 125.3; p = 0.01), respectively. The microcrystallization index of the RV in patients with furuncles in the maxillofacial region and neck from the first group, on the fifth day after the initial surgical treatment of the infectious and inflammatory focus and the start of complex anti-inflammatory treatment, was 1.83 (1.75-2.00). The second group patients had the microcrystallization index of the RV 1.75 (1.67-1.83). Moreover, the indicators showed a significant difference when comparing with each other (U = 122.6; p = 0.05). At the same time, when comparing with the result of healthy individuals, the first group retained significant differences (U = 120.0; p = 0.04), and the second group did not have significant differences with the control (U = 168.3; p = 0.97). The results obtained in the study confirmed the possibility of using the oral fluid microcrystallization indices for diagnosis, predicting the course of infectious-inflammatory process in individuals with boils in the maxillofacial region and neck and prove the benefits of using electroacupuncture in the complex of postoperative treatment in this group of patients. Conclusion. The presented research results are the basis for further development of tests based on qualitative and quantitative assessment of microcrystallization of biological fluids of the patient's body for predicting and evaluating the effectiveness of treatment in patients with infectious and inflammatory diseases of the maxillofacial region and neck in order to determine the direction of the process as early as possible (preclinical) and if necessary, timely correction of treatment and rehabilitation procedures.

Keywords: furuncle, no-odontogenic inflammatory process, oral fluid, microcrystallization, physiotherapy, electroacupuncture

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