ISSN 2415-3060 (print), ISSN 2522-4972 (online)
  • 22 of 48
Up
УЖМБС 2018, 3(2): 127–133
https://doi.org/10.26693/jmbs03.02.127
Clinical Medicine

Children Urinary System Organs Pathology in Kharkiv Region: Risk Factors and Development Prognosis

Sorokina I. V., Myroshnychenko M. S., Kapustnyk N. V., Arseniev O. V. 2
Abstract

Urinary system organs diseases in children relate to the actual problems of medical science and practice in Ukraine and other countries of the world. It is very important to conduct the epidemiological researches aimed at studying the prevalence of these diseases, identifying risk factors with the further calculation of the diseases development prognosis. This will help improve the medical care of children with urinary system organs pathology. The purpose of the study was to determine the risk factors and the prognosis of the urinary system organs diseases in the children of Kharkiv region. The material of the study included information about the child sex, weight and length of the child’s body at birth, age of his/her mother’s sexual life beginning, parents’ bad habits, nature of parents work, abortions in his/her mother’s anamnesis, characteristics of the course of pregnancy and parturition, genital and extragenital pathology in mothers, etc. This information was obtained by questioning the parents whose children were healthy and have different urinary system organs diseases. Statistical methods of investigation were used. The authors found that the risk factors for the development of urinary system organs pathology in the children of Kharkiv region were decreased in comparison with physiological norm weight and length of a child’s body at birth, smoking and unemployment of their parents, abortions in mothers’ anamnesis, complications during pregnancy (placental insufficiency and preeclampsia) and parturition (detachment of placenta and abnormalities in labor), genital and extragenital pathology (urinary system organs diseases). On the basis of general discriminant models, we constructed a statistically significant model for forecasting the possibility of congenital or acquired pathology of the urinary system organs development in children. This method has a high accuracy of prognosis. The proposed method of prognosis can be used after the childbirth or after a child’s discharge from the hospital with the purpose of assigning this child to the risk group for the development of congenital or acquired pathology of the urinary system, determining the further observation tactics, as well as the medical and preventive measures volume. Conclusions. In the course of the study, the risk factors for the development of the children urinary system pathology in Kharkiv region were identified. On the basis of general discriminant models, we constructed a statistically significant model for predicting the developmental pathology of this system’s organs, as well as its nature (congenital or acquired).

Keywords: risk factors, prognosis, pathology of the urinary system organs, children, Kharkiv region

Full text: PDF (Ukr) 211K

References
  1. Halafjan AA. Sovremennye statisticheskie metody medicinskih issledovanij. M: Izdatel'stvo LKI, 2008. 320 s. [Russian]
  2. Ignatova MS. Aktual'nye problemy nefrologii detskogo vozrasta v nachale XXI veka. Pediatrija. 2007; 86 (6): 6-13. [Russian]
  3. Marushko RV. Faktory ryzyku ta prognozuvannja rozvytku funkcional'nyh i hronichnyh zapal'nyh zahvorjuvan' kyshechnyku v ditej rann'ogo viku. Perinatologija i pediatrija. 2014; 1 (57): 51−5. [Ukrainian]
  4. Muratov GR, Kolibaeva TF, Gonchar' MA, Sorokina IV, Miroshnichenko MS. Nozologicheskaja struktura patologi organov mochevoj sistemy u detskogo naselenija Har'kovskoj oblasti. Problemy bezperervnoi' medychnoi' nauky ta praktyky. 2016; 3: 22−8. [Russian]
  5. Ruda VI. Riven' invalidnosti pry zahvorjuvannjah organiv sechovydil'noi' systemy u ditej Hmel'nyc'koi' oblasti. Sovremennaja pediatrija. 2015; 4 (68): 53−6. [Ukrainian]
  6. Sorokina IV, Markovskij VD, Borzenkova IV, Miroshnichenko MS, Pliten' ON. Morfologicheskie osobennosti glomeruljarnogo apparata pochek plodov i novorozhdennyh pri dejstvii razlichnoj gipoksii v jeksperimente. Morfologija. 2016; 10 (3): 267−72. [Russian]
  7. Sorokina IV, Miroshnichenko MS, Kapustnik NV, Arsen'ev AV. Faktory riska razvitija patologii organov mochevydelitel'noj sistemy u detej Har'kovskoj oblasti. Liky Ukrai'ny pljus. 2017; 3 (32): 12−3. [Russian]
  8. Zhidkova OB, Kurzina EA, Ivanov DO, Petrenko JuV. Vozmozhnosti prognozirovanija razvitija kriticheskih sostojanij u novorozhdennyh v zavisimosti ot sostojanija zdorov'ja materi. Vestnik Rossijskoj voenno-medicinskoj akademii. 2012; 4 (40): 213−6. [Russian]
  9. Kaspar CDW, Bholah R, Bunchman TE. A review of pediatric chronic kidney disease. Blood Purification. 2016; 41: 211−7. https://www.ncbi.nlm.nih.gov/pubmed/26766175. https://doi.org/10.1159/000441737