The purpose of the study is to determine the clinical significance, frequency and characteristics of chronic pancreatitis combined with gastroduodenal and biliary systems disease. The object of study - chronic pancreatitis and its combination with gastroduodenal and biliary zone diseases. Methods: objective, laboratory, instrumental and functional, using endoscopic, ultrasonographic and radiological techniques, questionnaire GSRS, determines the quality of life of the patient. The questionnaire includes 15 questions, of which 6 are formed of scales (scale in the pain, reflux syndrome, dyspeptic, constipation syndrome, total scale score). Performance scales ranging from 1 to 7 balls, the highest number of points indicates the worst quality of life. Clinically significant taking difference in 0.5 balls. Results and discussion. The study involved 112 people aged 16 to 62 years with chronic pancreatitis (CP). Chronic pancreatitis (CP) was diagnosed in 53 patients with chronic relapsing pancreatitis (CRP) - 59 patients. Flow duration was ranged from 3 to 10 years. The combination of CP and diseases of gastroduodenal zone of the digestive tract was observed in almost 82.1% of the primary treatment of the patients. Alcoholic CP detected in 37.5% cases, the secondary lesion factor of the pancreas due to gastrointestinal diseases transferred earlier, or proceeding parallel noted in 61.6% of patients. In the study of quality of life according to the questionnaire GSRS found that pain dominated at 77.5%, dyspeptic - at 18.1%, reflux syndrome and constipation troubled by 12.5% of patients. Significantly fewer patients indicated periodically arise diarrhea (5 patients (9.09%)). Most abdominal pain scales were increased in patients with acid-related diseases course. With prolonged duration 10 years, CP and availability trophological syndrome indicators significantly reduced. It was concluded that the combination of chronic pancreatitis with gastroduodenal diseases and biliary zones diseases often changes the clinical symptoms, which prolongs the verification of the diagnosis of the basic disease.

Keywords: chronic pancreatitis, acid disorders, diseases of the gallbladder and biliary tract, quality of life

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