The purpose of the study was to evaluate the effectiveness of comprehensive treatment of generalized periodontitis in young people with primary hypothyroidism. Materials and methods. Comprehensive treatment of chronic generalized periodontitis was performed on 110 patients aged 25-44 years, who were divided into treatment groups: the main group – 55 patients with hypothyroidism, who were treated using the developed treatment and prevention complex; and a control group, which included 55 patients with hypothyroidism, where treatment was carried out in accordance with the "Protocols of medical care of the Ministry of Healthcare of Ukraine" in the specialty "Therapeutic Dentistry". Clinical evaluation of the effectiveness of treatment was performed according to the criteria: "normalization", "improvement", "progression". Results and discussion. According to the results of the research, after the complex treatment of generalized periodontitis according to the developed scheme in patients of the main group, a steady improvement in the condition of periodontal tissues both in the near and long term was shown. After 1 month, "normalization" of periodontal tissue was observed in 29 patients (52.73 ± 6.79 %), "improvement" occurred in 18 patients (32.73 ± 6.38 %), "progression" – in 8 patients (14.54 ± 4.79 %). During the 12-month follow-up period, the number of patients with "normalization" increased to 36 people (65.46 ± 6.47 %), but the number of patients with "progression" of inflammatory-dystrophic phenomena in the periodontium decreased to 5 people (9.09 ± 3.91 %). In the control group, the positive clinical dynamics as a result of traditional treatment was less pronounced and was observed only after a month, although the number of patients with elimination of inflammatory phenomena in dental tissues in the near future was significantly less than in the main group and was 20 people (36.37 ± 6.55 %). After 12 months, the number of patients in the control group for whom the treatment of generalized periodontitis by traditional methods was ineffective increased to 30 people (54.50 ± 6.77 %). Conclusion. The application of the developed scheme for the prevention and treatment of generalized periodontitis, which was the result of our own clinical and laboratory studies and included local measures and general appointments, has significantly improved the condition of periodontal tissues in patients with primary hypothyroidism. The effectiveness of the applied treatment and prevention complex was confirmed by clinical observations at all follow-up periods. In the control group, where conventional methods were used, the treatment of generalized periodontitis was ineffective
Keywords: primary hypothyroidism, young age, generalized periodontitis, treatment, prevention
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