ISSN 2415-3060 (print), ISSN 2522-4972 (online)
  • 36 of 59
JMBS 2020, 5(5): 278–284
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Diagnosticity of Coronavirus Infection as a Current Problem of the State

Panchenko O., Zavarzina A.

The article presents current data referring to the main types of laboratory diagnosticity of coronavirus infection associated with severe acute coronavirus respiratory syndrome (SARS-CoV-2), which has caused the pandemic, as defined by the World Health Organization in 2019. New viruses for people and the risks associated with them periodically remind countries about necessity to be always ready for emergencies in the field of biological safety. However, these risks may differ for different countries, so each country should develop its own national assessment based on a global risk assessment. Recently, the world's attention has been focused on the spread of the disease, which has been caused by the coronavirus SARS-CoV-2 and was first recorded in China, in the city of Wuhan. There are many rumors about the virus today. On the one hand, there is an oversaturation of the information space with reports about coronavirus, and on the other hand, one can mark the low level of public awareness. Under conditions of a pandemic, all countries, despite their different political status and economic potential, have focused their efforts on a common enemy, the acute respiratory disease COVID-19, caused by the SARS-CoV-2 coronavirus. The issue of coronavirus infection diagnosticity becomes extraordinary relevant. In terms of a review of the scientific literature, the main data of human coronavirus infections history include the epidemic of severe acute respiratory syndrome (SARS) and Middle Eastern respiratory syndrome (MERS) and the current pandemic COVID-19. The etiology of COVID-19, its epidemiology, pathogenesis, main clinical variants and their symptoms, classification by severity, methods of laboratory diagnosticity have been consistently described. To understand the trends in the development of a pandemic, it is extremely necessary to have a clear understanding of the immunological structure of the population with the determination of the proportion of persons with post-infectious immunity, since in the absence of specific immunoprophylaxis, population immunity can be a marker not only of the intensity of the epidemic process, but also of the prognosis of its development. Conclusion. The experience of humanity's struggle with biological threats indicates that success was achieved only under the condition of early diagnosis, correct therapy and prevention in the foci of diseases, aimed at their localization and elimination through the immediate implementation of primary anti-epidemic measures. Timely blocking of the spread of the causative agent of the infection allows you to effectively stop the development of any epidemic complications with the least medical and social losses in the optimal time frame. The use of time-tested standards of anti-epidemic protection is advisable in any emergency situation caused by pathogenic biological agents, including during the COVID-19 pandemic

Keywords: coronavirus infection, pandemic, laboratory diagnosticity

Full text: PDF (Ukr) 382K

  1. VOZ. Naymenovanye zabolevanyya, vyzvannogo koronavyrusom (COVID-19), y vyrusnogo vozbudytelya [Name of the disease caused by the coronavirus (CHOVID-19) and the viral pathogen]. [Russian]. 2020. Available from:
  2. Diagnostyka, likuvannya, profilaktyka uskladnen, intensyvna terapiya koronavirusnoyi infektsiyi (2019 ncov): tymchasovi metodychni rekomendatsiyi [Diagnostics, exhilaration, prevention of acceleration, intensive therapy of coronavirus infection (2019 ncov): team-hour methodical recommendations]. Natsionalna akademiya medychnykh nauk Ukrayiny. Kyiv; 2020. 49 s. [Ukrainian]
  3. Nakaz No722 Ministerstva okhorony zdorov'ya Ukrayiny vid 28.03.2020. Organizatsiya nadannya medychnoyi dopomogy khvorym na koronavirusnu khvorobu COVID -19 [Organization of medical aid for COVID-19 ailments for coronavirus disease]. 2020. [Ukrainian]
  4. An update on the epidemiological characteristics of novel coronavirus pneumonia (COVID-19). Special Expert Group for Control of the Epidemic of Novel Coronavirus Pneumonia of the Chinese Preventive Medicine Association. Zhonghua Liu Xing Bing XueZa Zhi. 2020; 41(2): 139-144. sn.0254-6450.2020.02.002
  5. Wang D, Hu B, Hu C, Zhu F, Liu X, Zhang J, et al. Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China. JAMA. 2020 Mar 17; 323(11): 1061-1069.
  6. Guan W, Ni Z, Hu Y, Liang WH, Ou CQ, He JX, et al. Clinical characteristics of 2019 novel coronavirus infection in China. N Engl J Med. 2020 Apr 30; 382(18): 1708-1720.
  7. Zhang JJ, Dong X, Cao YY, Yuan YD, Yang YB, Yan YQ, et al. Clinical characteristics of 140 patients infected by SARSCoV-2 inWuhan, China. Allergy. 2020 Jul; 75(7): 1730-1741.
  8. Liu K, Fang YY, Deng Y, Liu W, Wang MF, Ma JP, et al. Clinical characteristics of novel coronavirus cases in tertiary hospitals in Hubei Province. Chin Med J (Engl). 2020 May 5; 133(9): 1025-1031.
  9. Shen M, Peng Z, Xiao Y, Zhang L. Modelling the epidemic trend of the 2019 novel coronavirus outbreak in China. bioRxiv. 2020 Jan 25. Avaliable from:
  10. Wang W, Tang J, Wei F, Wang W. Updated understanding of the outbreak of 2019 novel coronavirus (2019-nCoV) in Wuhan, China. J Med Virol. 2020; 92(4): 441-447.
  11. Jin YH, Cai L, Cheng ZS, Cheng Zh-Sh, Cheng H, Deng T, et al. A rapid advice guideline for the diagnosis and treatment of 2019 novel coronavirus (2019-nCoV) infected pneumonia (standard version). Military Medical Research. 2020; 7(4).
  12. Chen N, Zhou M, Dong X, Qu J, Gong F, Han Y, et al. Epidemiological and clinical characteristics of 99 cases of 2019 novelcoronavirus pneumonia in Wuhan, China: a descriptive study. Lancet. 2020 Feb 15; 395(10223): 507-513.